We expect that consensus meetings, where researchers come together to discuss their theoretical viewpoints, prioritize the factors they agree are important to study, standardize their measures, and determine a smallest effect size of interest, will prove to be a more efficient solution to the lack of coordination and integration of claims in science than integrative experiments.

This paper explores the perceptions of academic staff and students to student cheating behaviours in online exams and other online assessment formats. The research took place at three Australian universities in July and August 2020 during the emergency transition to online learning and assessment in response to the COVID-19 pandemic. The study sought to inform decision making about the future of online exams at the participating universities. Quantitative and qualitative data were collected using online surveys. The findings of the study (...) led to seven key observations, most notably the need to redefine the characteristics of academic misconduct to account for changes wrought to examinations in a digital world. The study concludes with lessons learned in relation to enhancing academic integrity in digital examinations and assessments. (shrink)

In recent years, a significant body of literature has emerged on the subject of epistemic injustice: wrongful harms done to people in their capacities as knowers. Up to now this literature has ignored the role that attention has to play in epistemic injustice. This paper makes a first step towards addressing this gap. We argue that giving someone less attention than they are due, which we call an epistemic attention deficit, is a distinct form of epistemic injustice. We begin by (...) outlining what we mean by epistemic attention deficits, which we understand as a failure to pay someone the attention they are due in their role as an epistemic agent. We argue that these deficits constitute epistemic injustices for two reasons. First, they affect someone’s ability to influence what others believe. Second, they affect one’s ability to influence the shared common ground in which testimonial exchanges take place. We then outline the various ways in which epistemic attention deficits harm those who are subject to them. We argue that epistemic attention deficits are harms in and of themselves because they deprive people of an essential component of epistemic agency. Moreover, epistemic attention deficits reduce an agent’s ability to participate in valuable epistemic practices. These two forms of harm have important impacts on educational performance and the distribution of resources. Finally, we argue that epistemic attention deficits both hinder and shape the development of epistemic agency. We finish by exploring some practical implications arising from our discussion. (shrink)

This study will be of interest to anyone concerned with a critical appraisal of mental health service users’ and carers’ participation in research collaboration and with the potential of the postcolonial paradigm of cultural safety to contribute to the service user research (SUR) movement. The history and nature of the mental health field and its relationship to colonial processes provokes a consideration of whether cultural safety could focus attention on diversity, power imbalance, cultural dominance and structural inequality, identified as barriers (...) and tensions in SUR. We consider these issues in the context of state‐driven approaches towards SUR in planning and evaluation and the concurrent rise of the SUR movement in the UK and Australia, societies with an intimate involvement in processes of colonisation. We consider the principles and motivations underlying cultural safety and SUR in the context of the policy agenda informing SUR. We conclude that while both cultural safety and SUR are underpinned by social constructionism constituting similarities in principles and intent, cultural safety has additional dimensions. Hence, we call on researchers to use the explicitly political and self‐reflective process of cultural safety to think about and address issues of diversity, power and social justice in research collaboration. (shrink)

Las ideas de Michel Foucault han tenido una gran influencia en las ciencias de la educación. Los estudios acerca de la sociedad disciplinaria se han convertido en una referencia ineludible para pensar las dinámicas de la institución escolar. Sin embargo, esa influencia a menudo se reduce a su enfoque crítico y deconstructivo, sin elaborar adecuadamente los aspectos propositivos y la influencia constructiva que su teoría puede ofrecer. Estetrabajo parte de la hipótesis de que los últimos estudios del filósofo brindan un (...) marco conceptual sólido que va más allá la mera crítica hacia las relaciones de poder, aportando intuiciones relevantes para aplicar al campo educativo. Siguiendo esta lógica, en la presente propuesta se explorarán algunos conceptos claves del pensamientotardío de Foucault: régimen de verdad, prácticas de sí, psicagogia y parresía. Estos conceptos permitirán rastrear la importancia de los últimos trabajos de Foucault para pensar la tarea educativa. Dichos trabajos invitan a considerar la potencia de la filosofía, ya no solo para cuestionar las estructuras sedimentadas, sino también como una fuerza motivadora de procesos de transformación ética y posibilidades de invención para la trama vital delos individuos. En síntesis, la argumentación permitirá mostrar que la interpretación que el filósofo realiza tanto de la filosofía estoica como del cinismo a —través de la noción de parresía— proporciona pautas claras para aplicar al trabajo pedagógico y a la relación docente-alumno. (shrink)

In How Stereotypes Deceive Us, Katherine Puddifoot provides a convincing non-normative account of what stereotypes are, and of the conditions under which we appropriately rely on them in achieving our epistemic and ethical goals. In this paper, I focus on Puddifoot’s discussion of what she takes to be the non-prejudicial use of accurate stereotypes and their role in causing or perpetuating harm. Such use can cause harm but does not, on the face of it, appear to be wrongful in the (...) way that ordinary cases of prejudicially motivated use of stereotypes are. This raises a challenge for identifying when our use of such stereotypes might be unjust or wrongful (and why). In response, I first suggest that prejudice might be located within the context in which one uses a stereotype, rather than within the content of the stereotype itself. In this way, we can indeed distinguish prejudicial (and therefore wrongful) use of accurate stereotypes from non-prejudicial (innocent) use of accurate stereotypes. And second, I suggest that we also ought to question whether the stereotypes being invoked in all cases really are accurate, given the context and scope of application. (shrink)

On many prominent accounts, moral praise- and blameworthiness depend on the quality of will an agent manifests in their action. This paper draws attention to a pertinent but overlooked phenomenon: the manifestation of commendable and objectionable qualities of will in an action at once. By showing that all the manifested qualities of will have an effect on the agent's praise- and blameworthiness (i.e., on their action's moral worth), it is argued that quality of will theories need to provide an account (...) of this effect. An account according to which the manifested degrees of qualities of will cancel each other out and the praise- or blameworthiness is determined by the remaining quality of will is discussed and dismissed. Finally, it is argued that agents who manifest objectionable and commendable qualities of will at once are simultaneously both praise- and blameworthy for their actions. Actions can thus have ambivalent moral worth. (shrink)

Sustainability has become a powerful discourse, guiding the efforts of various stakeholders to find strategies for dealing with current and future social-ecological crises. To overcome the latter, we argue that sustainability discourse needs to be based on a critical-emancipatory conceptualization. Therefore, we engage two such approaches—environmental justice approaches informed by a plural understanding of justice and feminist political economy ones focusing on care—and their analytical potential for productive critique of normative assumptions in the dominant sustainability discourse. Both of these approaches (...) highlight aspects of sustainability that are particularly relevant today. First, although sustainable development was conceptualized from the outset based upon a twofold notion of justice (intra- and intergenerational), the integration of justice in the dominant sustainability discourse and praxis often manifests merely as a normative aspiration. Meanwhile, the environmental justice and care approaches offer conceptualizations of justice that can act as a powerful lever and as transformation-strategy. Second, the dominant sustainability discourse largely remains within a neoliberal economic framework that continues to promote economic growth as the means to reach prosperity while neglecting the bases of every economy: care work and nature. Its focus lies solely on paid work and the market economy. By integrating (a) social and ecological ‘reproductivity’ (unpaid care and subsistence work as well as nature) and (b) democratic processes for just distribution of environmental burdens and benefits, as well as participatory equity in relevant decision making, feminist political economy and environmental justice approaches offer substantial strategies towards building humane, just and caring societies. (shrink)

O presente artigo pode ser justificado como um breve panorama do debate entre modernidade e pós-modernidade em suas implicações ao campo da educação e formação humana, diante da emergência de nova humanidade, fruto do capitalismo tardio, com suas promessas não cumpridas, diante da colonização de todas as esferas, inclusive da própria educação. Assim, este trabalho visa a traçar alguns contornos do complexo liame entre modernidade e pós-modernidade, bem como a concepção de homem decadente, por um lado, e de homem emergente, (...) de outro, ante essa nova condição geracional. Para tal, o trabalho se constitui de uma pesquisa de metodologia teórico-conceitual, propondo-se como uma contribuição ao recorrente questionamento sobre a relevância das metanarrativas na formação humana, tomando como autores “estelares” Kant e Nietzsche, justificando, inclusive, uma espécie de pré-história do debate entre os metarrelatos. Daí, portanto, as escolhas conceituais deste artigo, que se deu por agenciamentos que possibilitassem a defesa de uma concepção vitalista, inerentemente criativa, como uma disciplina do pensamento indispensável a uma humanidade que se queira para além da mera reprodução erudita, do cinismo mercadológico ou, ainda, dos desígnios tecnocientíficos e rudeza materialista-determinista que rondam o tempo presente. Portanto, o artigo sugere que o novo paradigma em construção, ao se pautar por uma nova lógica, nos possibilita, considerando as críticas à modernidade, dar vazão a novo horizonte ético, que considere o homem em sua integridade. Ou seja, compreendido como “sujeito peninsular”, e não, como sonhava a modernidade, como homem “insular”, tido como sobrenatural, desenraizado do corpo e da natureza. Palavras-chave: Formação humana. Educação. Modernidade. Pós-modernidade. (shrink)

Resumo: Identificamos tensionamentos na confluência das ações filosóficas entre ensino de filosofia e pesquisa. Destacamos o movimento permanente dos filósofos na produção de conhecimento, haja vista que há forte tendência a um ensino dinâmico e continuamente revisado pelos achados providos pela pesquisa e adequado ao contexto escolar. Vislumbramos nesse encontro polos muitas vezes díspares, principalmente, pelo fato de a pesquisa filosófica frequentemente encontrar barreiras nas atividades de ensino, e vice-versa. Porém, entrevemos possibilidades de interações entre ensino de filosofia e pesquisa. (...) O primeiro, por exemplo, oferece problemas importantes à pesquisa enquanto esta retribui com sugestões e respostas, o que, no conjunto, pode resultar num desenvolvimento incomum ao campo da filosofia. Além da produção de conhecimento, ressaltamos contribuições nessa parceria como: importante divulgação da filosofia pautada em um saber melhor embasado, contribuição na formação das pessoas e de um projeto de nação avesso à pobreza de argumentação e ajuizamento daqueles que foram alijados desses ensinamentos. A aproximação do ensino e pesquisa em filosofia provoca busca da segunda a tomar o primeiro como seu objeto de interesse e, no panorama da complexidade do campo, tornar a filosofia do ensino de filosofia espaço fecundo para produção de conhecimento e ação impactantes nos contextos escolares. Palavras-chave: Ensino de Filosofia; Pesquisa; Produção de Conhecimento Teaching Philosophy and Research: field of tensions, collaboration and knowledge production Abstract: We identified tensions at the confluence of philosophical actions between teaching philosophy and research. We highlight the permanent movement of philosophers in the production of knowledge, given that there is a strong tendency towards a dynamic teaching and continuously reviewed by the findings provided by the research and appropriate to the school context. In this meeting, we envision poles that are often disparate, mainly because philosophical research often encounters barriers in teaching activities, and vice versa. However, we glimpse possibilities of interactions between teaching philosophy and research. The first, for example, poses important problems to research while it responds with suggestions and answers, which, on the whole, can result in an unusual development in the field of philosophy. In addition to the production of knowledge, we highlight contributions in this partnership such as: important dissemination of philosophy based on a better-grounded knowledge, contribution to the formation of people and a project of a nation averse to the poverty of argumentation and judgment of those who were excluded from these teachings. The approximation of teaching and research in philosophy provokes the search for the second to take the first as its object of interest and, in the context of the complexity of the field, to make the philosophy of teaching philosophy a fertile space for the production of knowledge and impacting action in school contexts. Key-words: Teaching Philosophy; Research; Knowledge Production Enseñanza de la Filosofía y Investigación: campo de tensiones, colaboración y producción de conocimiento Resumen: Identificamos tensiones en la confluencia de acciones filosóficas entre la enseñanza de la filosofía y la investigación. Destacamos el movimiento permanente de los filósofos en la producción de conocimiento, dado que existe una fuerte tendencia hacia una enseñanza dinámica y continuamente revisada por los hallazgos que brinda la investigación y adecuada al contexto escolar. En este encuentro visualizamos polos muchas veces dispares, principalmente porque la investigación filosófica muchas veces encuentra barreras en la actividad docente, y viceversa. Sin embargo, vislumbramos posibilidades de interacciones entre la enseñanza de la filosofía y la investigación. La primera, por ejemplo, plantea importantes problemas a la investigación mientras responde con sugerencias y respuestas, lo que, en conjunto, puede resultar en un desarrollo inusual en el campo de la filosofía. Además de la producción de conocimiento, destacamos aportes en esta alianza como: importante difusión de la filosofía basada en un conocimiento mejor fundamentado, aporte a la formación de personas y proyecto de nación adversa a la pobreza de argumentación y juicio de aquellos que estaban excluidos de estas enseñanzas. La aproximación de la enseñanza y la investigación en filosofía provoca la búsqueda de que la segunda tome a la primera como su objeto de interés y, en el contexto de la complejidad del campo, hacer de la filosofía de la enseñanza de la filosofía un espacio fértil para la producción de conocimiento y acción impactantes en los contextos escolares. Palavras-clave: Enseñanza de la Filosofía; Búsqueda; Producción de Conocimiento Data de registro: 20/01/2023 Data de aceite: 24/01/2024. (shrink)

Research in diverse populations has often found that thin media images negatively affect women’s state body image, with many women reporting lower body satisfaction after exposure to pictures of thin models than before exposure. However, there is evidence that theistic affirmations might buffer against the negative effect of media on body image. Furthermore, based on cross-sectional and correlation analyses, religiosity and the Islamic body covering are discussed as protective factors against a negative trait body image. However, there is no experimental (...) research on veiled Muslim women’s state body image. Therefore, the current study experimentally investigated whether the body satisfaction of veiled Muslim women (n = 66) decreased after exposure to thin media images compared to pictures of furniture as a control condition. Christian women (n = 90) and atheist women (n = 74) were included as control groups, and participants were randomly assigned to the two conditions. Prior to the experimental session, participants’ trait body image was assessed using an online questionnaire comprising questions about body satisfaction, thin-ideal internalization, pressure to be thin, and physical appearance comparisons. The results showed that body satisfaction decreased in the experimental condition and not in the control condition, but no significant differences in pre-post changes were found between the three groups. However, in the experimental condition, veiled Muslim women reported a more positive state body image than did Christian women. Moreover, veiled Muslim women had a more positive trait body image than did Christian women and atheist women. Thus, veiled Muslim women reported lower levels of thin-ideal internalization, pressure to be thin, and physical appearance comparisons than did Christian women and atheist women. As the pre-post changes in body satisfaction did not differ between the three groups, veiling might not buffer against the negative effect of thin media images on state body image. Nevertheless, given the more positive trait body image of veiled Muslim women compared to Christian and atheist women, veiling might positively influence body image in the longer term. (shrink)

Performative accounts of personhood argue that group agents are persons, fit to be held responsible within the social sphere. Nonetheless, these accounts want to retain a moral distinction between group and individual persons. That: Group-persons can be responsible for their actions qua persons, but that group-persons might nonetheless not have rights equivalent to those of human persons. I present an argument which makes sense of this disanalogy, without recourse to normative claims or additional ontological commitments. I instead ground rights in (...) the different relations in which performative persons stand in relation to one another. (shrink)

The use of genetic engineering is increasingly discussed for nature conservation. At the same time, recent animal ethics approaches debate whether humans should genetically engineer wild animals to improve their welfare. This paper examines if obligations towards wild sentient animals require humans to genetically engineering wild animals, while arguing that there is no moral need to do so. The focus is on arguments from animal ethics, but they are linked to conservation ethics, highlighting the often neglected overlap between the two (...) fields. The paper emphasizes that a) the benefits of genetic engineering are overestimated and at the same time harms from its development and use underestimated, b) the assumption that genetic engineering is an appropriate ‘last resort’ tool is wrong, c) many arguments in favor of genetic engineering are based on an inadequate understanding of ecology and biotechnological processes, and d) the debate downplays the importance of self-determination for wild animals. (shrink)

En dépit de l’instauration d’un gouvernement calviniste dès la fin du XVIe siècle dans les Provinces-Unies, les catholiques y sont restés nombreux pendant le XVIIe siècle. Si les crises iconoclastes ont pu freiner la commande de tableaux d’église, les huiskerken (églises-maisons) et les schuilkerken (églises-cachées) furent rapidement décorées d’au moins un tableau d’autel, selon l’usage légitime des images réaffirmé par le concile de Trente. L’étude des collections a également rappelé la place des tableaux religieux dans les intérieurs catholiques. Dans ce (...) contexte confessionnel singulier, il convient de s’interroger sur la sensibilité catholique qui pouvait s’exprimer dans les tableaux sacrés peints dans les Provinces-Unies au XVIIe siècle. Au-delà de leurs fonctions didactiques évidentes, les peintures pour les milieux catholiques pouvaient-elles aussi satisfaire le sens de la vue? Dans quelle mesure la sensibilité catholique s’exprime, non pas seulement dans les choix iconographiques, mais aussi à travers les qualités plastiques des œuvres? (shrink)

Considerable heterogeneity among pediatric chronic pain patients may at least partially explain the variability seen in the response to behavioral therapies. The current study tested whether autistic traits and attention-deficit/hyperactivity disorder symptoms in a clinical sample of children and adolescents with chronic pain are associated with socioemotional and functional impairments and response to acceptance and commitment therapy treatment, which has increased psychological flexibility as its core target for coping with pain and pain-related distress. Children and adolescents aged 8–18 years were (...) recruited. Patients and their parents completed questionnaires pre- and post-ACT of 17 sessions. Correlational analyses and mixed-effects models were used to assess the role of autistic traits and ADHD symptoms in pretreatment functioning and ACT-treatment response. Outcome variables were degree to which pain interfered with daily activities, socioemotional functioning, psychological inflexibility, and pain intensity. Autistic traits and ADHD symptoms, pain frequency, and pain duration were measured at pretreatment only. Higher autistic traits were associated with greater pain interference, higher depression, and greater psychological inflexibility. Higher ADHD symptomatology was associated with greater pretreatment pain interference, lower emotional functioning, greater depression, and longer duration of pain. Across patients, all outcome variables, except for sleep disturbances and school functioning, significantly improved from pre- to post-ACT. Higher autistic traits were associated with greater pre- to post-ACT improvements in emotional functioning and sleep disturbance and non-significant improvements in pain interference. ADHD symptomatology was not associated with treatment outcome. The current results showed that neuropsychiatric symptoms in pediatric chronic pain patients are associated with lower functioning, particularly pain interfering with daily life and lower socioemotional functioning. The results suggest that not only pediatric chronic pain patients low in neuropsychiatric symptoms may benefit from ACT, but also those high in autism traits and ADHD symptoms. With the present results in mind, pediatric chronic pain patients higher in autistic traits may actually derive extra benefit from ACT. Future research could assess whether increased psychological flexibility, the core focus of ACT, enabled those higher in autism traits to cope relatively better with pain-related distress and thus to gain more from the treatment, as compared to those lower in autism traits. Moreover, to address specific effects of ACT, inclusion of an appropriate control group is key. (shrink)

ABSTRACTIn Democracy for Realists, Christopher Achen and Larry Bartels argue provocatively that the public falls far short of ideals of democratic citizenship, and they turn to political psychology to explain the empirics of mass political behavior. But their model of group identity fails to shed much light on the origins of political behavior and gives members of the public less credit than they deserve, for three reasons. First, group politics is not a hollow exercise; it depends on the identification of (...) a collective grievance that has a potential political solution. Second, concerns about group economics, status, and respect are more likely than individual economic considerations to animate political behavior, yet the former concerns are no less rational than the latter. Third, individuals vary in how strongly they identify with politically relevant groups, masking considerable variation in the degree to which group affiliations shape political behavior. Therefore, group identification is not a monolithic, irrational force that affects people regardless of their perceptions of political reality. (shrink)

Transgender and gender diverse (TGD) youth are currently being targeted by global anti-trans legislation that would prevent their access to gender-affirming care even by healthcare providers willing to deliver it and who understand the importance of this support. It has been suggested in some studies that transness in young people is a result of peer contagion. As such their free will, authenticity and autonomy could be brought into question when accessing gender-affirming care. It is important to explore the relevance of (...) these concepts concerning the provision of gender-affirming care to TGD youth by nurses and other healthcare professionals. Nurses should challenge the notion held by some that these young people are not capable of knowing themselves or the level of treatment they require. They can do this by practising gender-affirming care determined by aspirational ethical values of beneficence, non-maleficence, autonomy and justice. (shrink)

Polycomb response elements (PREs) are regulatory switch elements that can direct the genes that they control to be either active or silenced. Once decided, this on or off state is maintained through subsequent cell divisions. We do not know how the switching works, or how it is copied to newly replicated chromosomes. Experiments that switch a silenced PRE to an active state have provided insights into both questions. A PRE switched experimentally can remember its previously silenced state and return to (...) it after several cell divisions. In the most recent study of this phenomen on,(1) the data show that several distinct variables affect the ability of PREs to “remember” and restore their previous state. The authors' interpretation of these results is discussed here. BioEssays 23:566–570, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

The article outlines a meditation on the strategic structure of space, on the tactical definition of the relations of interiority/exteriority, on the processual nature of identifications – i.e. on the way an event summons the subject within a group while drawing both the subject as belonging to the group and the group as belonging to that subject. Two texts guide this reflection: ‘Space’ by Georges Bataille and The Groupist by Jorge Luis Borges and Adolfo Bioy Casares.

A meditation on specularity as paradigms of a theory of experience which informs every field of philosophy and human sciences, including contemporary neurosciences. And a meditation, starting from neurosciences and mirror neurons, on the different readings of this paradigm of specularity and specularization. In particular, on that “second” reading of specularization, which suggests that the mirror is not an instrument of representation but of expression, not a device of adaquation but of creation. It is an hypothesis that Merleau-Ponty, facing the (...) very same problems contemporary neurosciences are confonted to, reactivates in an increasingly systematic way in his later years, drawing from a tradition which we try here to reconstruct. From Merleau-Ponty to Bergson, from Bergson to Leibniz, this second reading of specularity contains a possibility which is still fruitful and which neurosciences themselves could adopt in order to reconsider in a new perspective the evidences they have considered until now from the point of view of a first reading of specularity. This second reading of specularity suggests that it is not so much necessary to explain how one subject comprehends the other, but how both subjects are comprehended within the transcendental space of what we could call an event. Empathy is not so much a syntonization among subjects, but subjects are a partial and local desyntonization of that empathic system we should place as the beginining and not at the end of the process. Consciousness does not represent the other consciousness, but they express in a simultaneous and specular diffraction the fundamental unity of an event which is every time unique and impersonal. (shrink)

Virtual assistants (VAs), like Amazon’s Alexa, Google’s Assistant, and Apple’s Siri, are on the rise. However, despite allegedly being ‘assistants’ to users, they ultimately help firms to maximise profits. With more and more tasks and leeway bestowed upon VAs, the severity as well as the extent of conflicts of interest between firms and users increase. This article builds on the common law field of fiduciary law to argue why and how regulators should address this phenomenon. First, the functions of VAs (...) resemble established fiduciaries, namely mandataries when they perform tasks on behalf of users, and increasingly advisors whenever they provide recommendations or suggestions. Second, users grant firms deploying VAs ever more discretion over their economic, and more and more significant non-economic interests, such as their health or finances. This delegation of power renders users vulnerable to abuse of power and inadequate performance by firms deploying VAs. Moreover, neither specification or monitoring nor market forces are alternatives that can sufficiently protect users. Thus, regulation is needed, departing from the recognition of the relationship between firms deploying VAs and users as a fiduciary relationship. In the EU, this could be realised through fiduciary requirements for VAs. First and foremost, to adequately protect users from abuse of power by firms deploying VAs, the core fiduciary duty of loyalty should be converted into corresponding fiduciary requirements for VAs, obliging firms to align VAs with their users. (shrink)

The Surprise Exam Paradox is well-known: a teacher announces that there will be a surprise exam the following week; the students argue by an intuitively sound reasoning that this is impossible; and yet they can be surprised by the teacher. We suggest that a solution can be found scattered in the literature, in part anticipated by Wright and Sudbury, informally developed by Sorensen, and more recently discussed, and dismissed, by Williamson. In a nutshell, the solution consists in realising that the (...) teacher's announcement is a blindspot that can only be known if the week is at least 2 days long. Along the way, we criticise Williamson's own treatment of the paradox. In Williamson's view, the Surprise is similar to the Paradox of the Glimpse and, because of their similarities, both these paradoxes ought to receive a uniform treatment-one that involves locating an illicit application of the KK Principle. We argue that there's no deep analogy between the Surprise and the Glimpse and that, even if there were, the Surprise reasoning reaches a paradoxical conclusion before the KK Principle is used. Rather, in both the Surprise and the Glimpse, the blame should be put on other epistemic principles-respectively, a knowledge retention and a margin for error principle. (shrink)

For stem cells, life is full of potential: they have a high capacity to proliferate and a wide choice of future identities. When they differentiate, cells leave behind this freedom and become ever more committed to a single fate. Intriguingly, the Polycomb and Trithorax groups of proteins are vital to the very different natures of both stem cells and differentiated cells, but little is known about how they make the transition from one cell type to the other. A recent paper1 (...) throws light on this mystery, showing that the Polycomb proteins dramatically change their behaviour at a crucial moment of differentiation. BioEssays 28: 330–334, 2006. © 2006 Wiley Periodicals, Inc. (shrink)

Opponents and proponents alike of the freedom of the UK press to print prejudicial content about marginalised groups typically frame the debate in classic ‘free speech’ vs ‘harm principle’ terms. Those in favour of press freedom argue that the print press' right to freedom of expression beats any perceived or actual harm caused, and those against argue the opposite. Predictably, little progress is made in either party convincing the other. I suggest that we ought to instead ask, what grounds the (...) freedom of the press? I propose that one plausible answer is: the value of agential epistemic participation. And I argue that we cannot uphold that value at the same time as permitting discriminatory reporting against collectives of individuals. This offers a strong basis from which to argue for a change in UK press regulatory policy, to allow discrimination claims against groups of individuals to be heard. Further, when we consider the role of epistemic participation in one’s ability to perform as a person, we ought to find that most complaints will in practice find in the favour of the group in question, rather than the PPM. (shrink)

Ethical concerns regarding agricultural practices can be found to co-evolve with technological developments. This paper aims to create an understanding of ethics that is helpful in debating technological innovation by studying such a co-evolution process in detail: the development and adoption of the milking robot. Over the last decade an increasing number of milking robots, or automatic milking systems (AMS), has been adopted, especially in the Netherlands and a few other Western European countries. The appraisal of this new technology in (...) ethical terms has appeared to be a complicated matter. Compared to using a conventional milking parlor, the use of an AMS entails in several respects a different practice of dairy farming, the ethical implications and evaluation of which are not self-evident but are themselves part of a dynamic process. It has become clear that with its use, the entire practice of dairy farming has been reorganized around this new device. With a robot, cows must voluntarily present themselves to be milked, whereby an ethical norm of (individual) freedom for cows can be seen to emerge together with this new technology. But adopting a robot also implies changes in what is considered to be a good farmer and an appropriate relation between farmer and cow. Through interviews, attending “farmers’ network” meetings in the Netherlands, and studying professional literature and dedicated dairy farming web forums, this paper traces the way that ethical concerns are a dynamic part of this process of rearranging a variety of elements of the practice of dairy farming. (shrink)

Introduction:The effects of specific suggestions are usually studied by measuring parameters that are directly addressed by these suggestions. We recently proposed the use of a uniform, unrelated, and objective measure like maximal muscle strength that allows comparison of suggestions to avoid nocebo effects and thus to improve communication. Since reduced breathing strength might impair respiration and increase the risk of post-operative pulmonary complications, the aim of the present study was to evaluate the effects of the suggestions on respiratory muscle power. (...) Both the identification and neutralization of negative suggestions in the clinical context and stimulating suggestions could improve breathing force, a predictor of physical fitness and convalescence.MethodsIn 50 healthy, adult volunteers, respiratory muscle strength was measured by maximal inspiratory and expiratory pressures, as well as by maximal inspiratory and expiratory flows. Baseline was compared to values after application of eleven suggestions, five out of clinical context, including memory of negative or positive past, risk information for informed consent, and a non-verbal suggestion. Six stimulating suggestions included self-affirmation, empowering words, a heroic mirror image, and an imagination.ResultsAll suggestions showed an impact on respiratory muscle strength, indicating placebo and nocebo effects. No single parameter could represent the breathing force in its complexity, however, trends and different specific aspects of it were measured. The strongest reaction was observed with the recall of a previous negative situation resulting in a reduction in expiratory flow to 96.1% of baseline. After risk information, a decrease was observed in three of the parameters, with the highest extend in expiratory pressure by 4.4%. This nocebo effect was neutralized by adding positive aspects to the risk information. Every intended strengthening suggestion resulted in statistically significant increases of at least one parameter, with changes of up to 10%, indicating placebo effects. Here, expiration was more affected than inspiration. Sex was the only influencing factor reaching statistical significance, with stronger reactions in women.ConclusionRespiratory muscle strength proved to be sensitive to suggestions with clinical context, as well as suggestions intended for stimulation. With this objective measurement, evaluation, and comparison of different suggestions is possible to help avoid nocebo effects. The demonstrated effect of supporting suggestions can be followed up and used in clinical practice. (shrink)

The history of political philosophy is marked by a conception of politics as inherently tragic. As such, it has hardly ever been systematically contrasted with the other model of dramatic art, comedy. In this article, I explore the relation between Hegel's twofold notion of drama as an ordered genre of disorder – what he considers to be the highest form of self-reflective art – and the post-foundational concept of radical democracy. After outlining the interplay between order and disorder in post-foundationalist (...) theories of political difference, I summarize the way in which the steps of Hegel's poetics consecutively build on each other and elaborate the role of the dramatic genres. By means of a genealogical reconstruction of the respective concepts of democracy and drama, I demonstrate the extent to which these two methodologies correspond to poetic and political order formation in a structural homology. This conceptualization concludes with the assertion of a constitutive dramatization of political modernity which does not, however, culminate in the concept of political tragedy but points towards a still-to-be-realized, comically ordered democracy. (shrink)

This article offers a distinctive way of grounding the regulative duties held by social media companies (SMCs). One function of the democratic state is to provide what we term the right to democratic epistemic participation within the public sphere. But social media has transformed our public sphere, such that SMCs now facilitate citizens’ right to democratic epistemic participation and do so on a scale that was previously impossible. We argue that this role of SMCs in expanding the scope of what (...) counts as fair democratic epistemic participation, and in becoming the providers of access to the digital public sphere, brings with it duties of regulation. (shrink)

This chapter draws on experiences of being identified as the financial precariat in the UK to argue that testimonial interactions between those who are in financially precarious conditions, and agents of the street-level organisations responsible for provision of health services, security and welfare, are at systematic risk of being dangerously epistemically dehumanising. This epistemic dehumanisation differs from instances of testimonial injustice in which the speaker retains some element of epistemic subjectivity and control over her contribution to the interaction. We are (...) epistemically dehumanised when we are expected to act as epistemic agents in testimonial contexts which are of great importance to us, while being met by an audience which is heavily predisposed against hearing us speak. The conditions under which this is likely to take place are strongly predicted for people marked out as poor, in their interactions with street-level organisations and their agents. As a result, the speaker who is often in serious need of help, is left epistemically disenfranchised, and at severe and probable risk of material harm. (shrink)

Contemporary animal ethics mainly developed due to the human treatment of farmed animals. Thereby, the following questions were neglected: If nonhuman animals are part of the moral community, what does this mean for human obligations towards wild animals? Must these be the same as towards domesticated animals? Could an unequal treatment be justified or would it be arbitrarily? Recent animal ethicists are dealing more and more with these questions. The work at hand discusses this topic intensively. It examines how 'classical' (...) theories of animal ethics can be applied to the question of how a proper treatment of wild animals should look like. It especially focusses on the approach of Clare Palmer and its implications on wild animals and so called followers of culture. Subsequently, the compiled results are applied to the topic of 'invasive species'. (shrink)

This article offers an entry into Spinoza's political philosophy for a popular audience. In it, I lay out what is–to me–most distinctive about his political philosophy: his deep disinterest in the question of the justifiability of political resistance.

De Dreu and Gross's distinction between attack and defense is complicated in real-world conflicts because competing leaders construe their position as one of defense, and power imbalances place status quo challengers in a defensive position. Their account of defense as vigilant avoidance is incomplete because it avoids a reference to anger which transforms anxious avoidance into collective and unified action.

This chapter explores Michel Foucault's contribution to a critical assessment of modern and contemporary psychiatric practice. It focuses firstly on the History of Madness : the social, political, cultural, epistemological construction of the object "psychiatric patient" and "psychiatric pathology"; the gradual historical shift from "madness" to "psychiatric pathology" and its social and epistemological consequences; the horizons and limits of the romantic task Foucault assumes on this basis ; the critique Jacques Derrida formulated about this project, and particularly about Foucault's reading (...) of Descartes. Secondly, it examines Foucault's course on Psychiatric Power, focusing on the sociopolitical consequences of this medicalization process: i.e., the construction of the object "psychiatric patient" as "disciplinated bodies", and the general context of this anthropological metamorphosis Foucault studied in his books Discipline and Punish, The Will to Knowledge, and in his course Naissance de la biopolitique. (shrink)

Il saggio intende sviluppare una fenomenologia della violenza, a partire dagli Scritti di Franco Basaglia, che ha studiato il problema della violenza nell’istituzione psichiatrica e ha riflettuto sulla questione in una prospettiva fenomenologica. La sua tesi fondamentale è stata che la violenza dell’istituzione consista in una sostituzione e in un’alienazione. Il corpo vissuto, l’identità originaria di una persona, le sue esperienze e i suoi pensieri sarebbero rimpiazzati da quelli dell’istituzione, che diverrebbe così il ‘corpo’ di quella persona. La fenomenologia di (...) Basaglia traccia quindi, al seguito di Husserl, un’opposizione netta tra esperienza vissuta e istituzione, soggettività e segno sociale, identità privata e marca culturale. Possiamo tuttavia accogliere questa opposizione tanto semplice e trasparente? E in caso negativo, se la violenza non potesse essere descritta come la semplice irruzione dell’istituzione nello spazio del soggetto, se questa irruzione dell’Altro fosse anzi costitutiva del soggetto stesso, come pensare la violenza? Come definire una ‘politica’ di questa violenza originaria?This essay tries to develop a phenomenology of violence. Its approach is based on the Writings of Franco Basaglia, who studied the phaenomenon of violence in the psychiatric institutions and reflected on this issue from a phenomenological point of view. His main theses was that institutional violence means substitution and alienation. The lived body, the originary identity of a person, his experiences and thoughts are replaced by those of the institution. The institution itself becomes the ‘body’ of that person. Basaglia’s phenomenology thus traces, with Husserl, a neat opposition between lived experience and institution, subjectivity and social sign, private identity and cultural mark. Can we trust this simple and transparent opposition? And if violence cannot be described as an irruption of the institution in the subject’s space, if this irruption of the Other is constitutive of the subject itself, how to define violence? And how to define a ‘politics’ of this originary violence? (shrink)

This chapter approaches the question of the possibility/impossibility of a ‘science of the soul’ and suggests that its impossibility coincides with its highest ‘possibility’. A series of objections is address to the idea of ‘comprehension’ that Dilthey and Jaspers adopted against positivistic psychology and philosophy—not so much to return to the positivistic viewpoint, as to promote the idea that only an ‘un-comprehensive’ science could be adequate to that object which is not an object: human singularity, maybe singularity itself. I use (...) Nicholas of Cusa’s theology ‘against’ the Dilthey-Jaspers theory of comprehension to suggest that a whole landscape of ‘human’ sciences become human by becoming ‘in-human’, ‘un-comprehensive’, and at the same time becoming practical, concrete techniques: Blanchot’s literary critique, Lacan’s psychoanalysis, Mauss’ economics, and Bataille’s sociology. (shrink)

El objetivo de este artículo es estudiar las llamadas Achaica de Polibio (2.37-70). Se propone dejar de lado indemostrables hipótesis, tanto sobre una escritura independiente, como también con respecto a la supuesta inserción tardía e inorgánica de este texto en las Historias. En cambio, se busca relacionar las Achaica con la situación histórica en Grecia en ca. 150 a.C. a fin de entender la construcción discursiva de una imagen internacional de los aqueos fundada en una fama histórica de pístis y (...) philanthropía como una respuesta del historiador aqueo a una situación amenazante contemporánea sobre la Confederación aquea por parte de Roma. (shrink)

The Cogito and the Mexican Salamander.Philosophy and the Rest of Sciences in the late Merleau-Ponty The article examines Merleau-Ponty’s almost parallel reading – in his last courses at the Collège de France – of the Cartesian cogito and the development of the Axolotl, the salamander studied by American biologist Coghill. My hypothesis is that the metaphysics of the cogito and the biology of the Axolotl represented for Merleau-Ponty two ways of access to the same discovery. Descartes came up against a (...) phenomenon, the cogito, which required the reshaping of metaphysics as a sort of (impossible) psychology of the event or the absolute. Within the field of anatomy, Coghill came up against a phenomenon, the embryogenesis of the Axolotl, which similarly required a sort of conversion of anatomy into embryology. Therefore, bios and psyché, “embryonality” and the cogito, would be nothing but the denomination of the objects that psychology and biology meet along their borders, names for what we could refer to as “event,” “continuum,” “becoming” or, according to an old but still suitable definition, “absolute.” This has countless consequences on the relationship between the so-called human sciences and the so-called natural sciences, their eternally missed dialogue, their false complementarity and the illusion that the famous “two cultures” do actually exist.Il Cogito e la lucertola messicana.La filosofia e il resto delle scienze nell’ultimo Merleau-Ponty L’articolo prende in esame la lettura quasi parallela che Merleau-Ponty svolge, negli ultimi corsi di lezione al Collège de France, del cogito cartesiano e dello sviluppo dell’Axolotl, la lucertola studiata dal biologo americano Coghill. La nostra ipotesi è che la metafisica del cogito, e la biologia dell’Axolotl, rappresentino agli occhi di Merleau-Ponty due modi d’accesso a una stessa scoperta. Dall’interno della metafisica, Descartes si imbatte in un fenomeno, il cogito appunto, che esige che la metafisica si istituisca come una sorta di (impossibile) psicologia dell’eventoo dell’assoluto. Tutta la metafisica sarebbe psicologia, cioè indicazione del luogo assoluto nel quale è inscritto ogni luogo. Dall’interno dell’anatomia, Coghill siimbatte in un fenomeno, lo sviluppo dell’embrione dell’Axolotl, che esige analogamente che tutta l’anatomia si risolva in embriologia. Il vivente sarebbe allora in generale questa condizione di gemmazione e autoorganizzazione, e l’embriologia sarebbe la scienza (impossibile) di questo divenire perfettamenteanoggettuale. Bios e psyché, “embrionalità” e cogito non sarebbero che i nomi di ciò che la psicologia e la biologia incontrano al loro confine, nomi di ciò che infilosofia si chiama evento, continuum, divenire, o, con un vecchio e adattissimo termine, assoluto. Il che comporta innumerevoli conseguenze circa il rapporto trale cosiddette scienze umane e le cosiddette scienze naturali, sul loro dialogo eternamente mancato, sulla loro falsa complementarietà, sull’illusione che si diano davvero le celebri “due culture”. (shrink)

This chapter brings together important contributions from geographers, historians, sociologists and media theorists, and looks at these through the lens of social philosophy on the nature of resistance and oppression, to articulate and understand both the positive and negative ways in which industrial nostalgia shapes present-day working-class identities. Celebrations of abandoned industrial sites have been criticised by some as inflicting a form of violence on working-class people (High and Lewis 2007), transforming sites of working-class loss into objects of nostalgic appreciation (...) in ways which marginalise those who worked there, and which close the past off from the working-class present (Lasch 1991). More positive views about industrial nostalgia argue that it provides a way to assert working-class pride in hostile environments, serving as a basis for present-day solidarity (Loveday 2014; Gibbs 2021). By examining this existing literature on deindustrialisation through a social philosophical perspective, our aim here is to shed some light on this phenomenon, in which industrial nostalgia can function both as a tool of oppression but also as a form of resistance against oppression. (shrink)

Several states in the United States of America and countries in Europe punish parents when their minor child commits a crime. When parents are being punished for the crimes committed by their children, it should be presumed that parents might be held responsible for the deeds of their children. This article addresses the question whether or not this presumption can be sustained. We argue that parents can be blamed for the crimes of their children, not because they have the duty (...) to control their children as is often maintained, but because they have the duty to assist their child to develop in such a way that s/he becomes a morally competent agent. (shrink)

A meditation on specularity as paradigms of a theory of experience which informs every field of philosophy and human sciences, including contemporary neurosciences. And a meditation, starting from neurosciences and mirror neurons, on the different readings of this paradigm of specularity and specularization. In particular, on that “second” reading of specularization, which suggests that the mirror is not an instrument of representation but of expression, not a device of adaquation but of creation. It is an hypothesis that Merleau-Ponty, facing the (...) very same problems contemporary neurosciences are confonted to, reactivates in an increasingly systematic way in his later years, drawing from a tradition which we try here to reconstruct. From Merleau-Ponty to Bergson, from Bergson to Leibniz, this second reading of specularity contains a possibility which is still fruitful and which neurosciences themselves could adopt in order to reconsider in a new perspective the evidences they have considered until now from the point of view of a first reading of specularity. This second reading of specularity suggests that it is not so much necessary to explain how one subject comprehends the other, but how both subjects are comprehended within the transcendental space of what we could call an event. Empathy is not so much a syntonization among subjects, but subjects are a partial and local desyntonization of that empathic system we should place as the beginining and not at the end of the process. Consciousness does not represent the other consciousness, but they express in a simultaneous and specular diffraction the fundamental unity of an event which is every time unique and impersonal. (shrink)

A meditation on specularity as paradigms of a theory of experience which informs every field of philosophy and human sciences, including contemporary neurosciences. And a meditation, starting from neurosciences and mirror neurons, on the different readings of this paradigm of specularity and specularization. In particular, on that “second” reading of specularization, which suggests that the mirror is not an instrument of representation but of expression, not a device of adaquation but of creation. It is an hypothesis that Merleau-Ponty, facing the (...) very same problems contemporary neurosciences are confonted to, reactivates in an increasingly systematic way in his later years, drawing from a tradition which we try here to reconstruct. From Merleau-Ponty to Bergson, from Bergson to Leibniz, this second reading of specularity contains a possibility which is still fruitful and which neurosciences themselves could adopt in order to reconsider in a new perspective the evidences they have considered until now from the point of view of a first reading of specularity. This second reading of specularity suggests that it is not so much necessary to explain how one subject comprehends the other, but how both subjects are comprehended within the transcendental space of what we could call an event. Empathy is not so much a syntonization among subjects, but subjects are a partial and local desyntonization of that empathic system we should place as the beginining and not at the end of the process. Consciousness does not represent the other consciousness, but they express in a simultaneous and specular diffraction the fundamental unity of an event which is every time unique and impersonal. (shrink)

Merleau-Ponty’s article, “La guerre a eu lieu”, contains, as has been said, a kind of new phenomenology of perception. Its research question could be formulated as follows. What prevented German-occupied France from perceiving the enemy as an enemy for so many months or years of alienating cohabitation? The “drôle de guerre” would, among other things, be linked to this singular perceptual impasse. An impasse that is as dramatic as instructive, since it shows that war and politics have nothing to do (...) with handling the friend/enemy dialectical opposition Carl Schmitt situated at the center of his philosophy. Rather, they have to do with handling an adialectical field in which that opposition is not yet delineated and perceptible, but is rather evolving in a continuity and ambiguity that constitute the real (and in this sense immoral) matter of politics and war. (shrink)

This article examines Merleau-Ponty’s idea of an “ontological psychoanalysis” and extends it in a close dialogue both internal to Merleau-Ponty (his reflection on fetishism and the Kleinian partial object, the phenomenology of hallucination, his dissolution of ontology and the resolution of the flesh in a framework of events or a becoming of becomings) and external to Merleau-Ponty: on the one hand, with Lacan and his Seminar X (the idea of the object little-a, its possible double reading as object-divergence and as (...) event of divergence always in progress); and, on the other hand, with the Bergson of Matter and Memory (his idea of the image in itself: in Lacanian language, a kind of splinter of the real, without relation, autistic, hallucinatory) and with the Bergsonian idea of philosophical gesture (that Merleau-Ponty himself takes up, as we know, in In Praise of Philosophy). The guiding idea is that a psychoanalytic process is an experimental ontology: experimentation with being and of being, and with a being that is the result of its own staging [mise en expérience], in its own becoming through experience and experimentations, in its own future as divergence and its own movement of diverging. And the idea is also that philosophy, or at least a certain idea of philosophy, that of Merleau-Ponty’s Praise, proceeds in the same direction.L’article interroge l’idée merleau-pontienne d’une « psychanalyse ontologique » et la prolonge dans un dialogue serré interne à Merleau-Ponty (sa réflexion sur le fétichisme et sur l’objet partiel kleinien, la phénoménologie de l’hallucination, la dissolution merleau-pontienne de l’ontologie et la résolution de la chair dans une trame d’événements ou un devenir de devenirs) et externe à Merleau-Ponty : d’un côté avec Lacan et son Séminaire X (l’idée d’objet petit a, sa double lecture possible comme objet-écart et comme événement d’un s’écarter toujours en cours) ; de l’autre côté avec le Bergson de Matière et mémoire (son idée d’image en soi : en langage lacanien, une sorte de scheggia de réel, sans relation, autistique, hallucinatoire) et avec l’idée bergsonienne de geste philosophique (que Merleau-Ponty lui-même reprend, comme on le sait, dans Eloge de la philosophie. L’idée directrice est qu’un parcours psychanalytique est une ontologie expérimentale : une expérimentation avec l’être et de l’être, et avec un être qui résulte de sa propre mise en expérience, dans son propre devenir par l’expérience et par les expérimentations, dans son propre advenir comme écart et son propre mouvement d’écartement. Et aussi, que la philosophie, ou au moins une certaine idée de la philosophie, celle de l’Eloge merleau-pontien, procède dans la même direction.L’articolo muove dall’idea merleau-pontyana di una “psicoanalisi ontologica” interrogandola e prolungandola in uno stretto dialogo interno a Merleau-Ponty (la sua riflessione sul feticismo e sull’oggetto parziale kleiniano, la fenomenologia dell’allucinazione, la dissoluzione merleau-pontyana dell’ontologia e la risoluzione della carne in una trama di eventi o un divenire di divenire) ed esterno a Merleau-Ponty: da un lato con Lacan e con il suo Seminario X (l’idea di oggetto a piccolo, la sua doppia lettura possibile come oggetto-scarto e come evento di uno scartarsi sempre in corso); dall’altro con il Bergson di Materia e memoria (la sua idea di immagine in sé: lacanianamente, una sorta di scheggia di reale, irrelato, autistico, allucinatorio) e con l’idea bergsoniana di gesto filosofico (che lo stesso Merleau-Ponty riprende, com’è noto, in Elogio della filosofia). L’idea guida è che un percorso psicoanalitico sia un’ontologia sperimentale: un esperimento con l’essere e dell’essere, e con un essere o di un essere risolto nel suo proprio sperimentarsi, nel suo proprio divenire per esperienze ed esperimenti, nel suo proprio accadere come scarto e nel suo proprio scartarsi. E che la filosofia, o almeno una certa idea di filosofia, quella dell’Elogio merleau-pontyano, proceda in analoga direzione. (shrink)

The article examines the main features of Merleau-Ponty’s philosophy of nature and, more specifically, the reasons that led it to some consonance with that of the young Simondon. At the center of this recognition, the question of processuality and the pre-Socratic suggestions about a philosophy of the elements. The aim is to derive a need, which, if it remained unfulfilled in Merleau-Ponty, was instead expressed in Simondon and in many contemporary philosophies of nature, e.g. that of Bruno Latour, to whom (...) some space is devoted. That is, the need to bring into focus that substantial indiscernibility between nature and technique, which becomes an evidence if one enters into the idea of process. It is to the ethical and political consequences of this indiscernibility that the article’s conclusions are dedicated. More precisely, these conclusions suggest that only a thought of the indiscernibility between nature and technology has ethical and political consequences, i.e. allows the design of a system of regulations capable of concretely and sustainably modulating the human impact on the planet. (shrink)

This article examines Merleau-Ponty’s idea of an “ontological psychoanalysis” and extends it in a close dialogue both internal to Merleau-Ponty (his reflection on fetishism and the Kleinian partial object, the phenomenology of hallucination, his dissolution of ontology and the resolution of the flesh in a framework of events or a becoming of becomings) and external to Merleau-Ponty: on the one hand, with Lacan and his Seminar X (the idea of the object little-a, its possible double reading as object-divergence and as (...) event of divergence always in progress); and, on the other hand, with the Bergson of Matter and Memory (his idea of the image in itself: in Lacanian language, a kind of splinter of the real, without relation, autistic, hallucinatory) and with the Bergsonian idea of philosophical gesture (that Merleau-Ponty himself takes up, as we know, in In Praise of Philosophy). The guiding idea is that a psychoanalytic process is an experimental ontology: experimentation with being and of being, and with a being that is the result of its own staging [mise en expérience], in its own becoming through experience and experimentations, in its own future as divergence and its own movement of diverging. And the idea is also that philosophy, or at least a certain idea of philosophy, that of Merleau-Ponty’s Praise, proceeds in the same direction.L’article interroge l’idée merleau-pontienne d’une « psychanalyse ontologique » et la prolonge dans un dialogue serré interne à Merleau-Ponty (sa réflexion sur le fétichisme et sur l’objet partiel kleinien, la phénoménologie de l’hallucination, la dissolution merleau-pontienne de l’ontologie et la résolution de la chair dans une trame d’événements ou un devenir de devenirs) et externe à Merleau-Ponty : d’un côté avec Lacan et son Séminaire X (l’idée d’objet petit a, sa double lecture possible comme objet-écart et comme événement d’un s’écarter toujours en cours) ; de l’autre côté avec le Bergson de Matière et mémoire (son idée d’image en soi : en langage lacanien, une sorte de scheggia de réel, sans relation, autistique, hallucinatoire) et avec l’idée bergsonienne de geste philosophique (que Merleau-Ponty lui-même reprend, comme on le sait, dans Eloge de la philosophie. L’idée directrice est qu’un parcours psychanalytique est une ontologie expérimentale : une expérimentation avec l’être et de l’être, et avec un être qui résulte de sa propre mise en expérience, dans son propre devenir par l’expérience et par les expérimentations, dans son propre advenir comme écart et son propre mouvement d’écartement. Et aussi, que la philosophie, ou au moins une certaine idée de la philosophie, celle de l’Eloge merleau-pontien, procède dans la même direction.L’articolo muove dall’idea merleau-pontyana di una “psicoanalisi ontologica” interrogandola e prolungandola in uno stretto dialogo interno a Merleau-Ponty (la sua riflessione sul feticismo e sull’oggetto parziale kleiniano, la fenomenologia dell’allucinazione, la dissoluzione merleau-pontyana dell’ontologia e la risoluzione della carne in una trama di eventi o un divenire di divenire) ed esterno a Merleau-Ponty: da un lato con Lacan e con il suo Seminario X (l’idea di oggetto a piccolo, la sua doppia lettura possibile come oggetto-scarto e come evento di uno scartarsi sempre in corso); dall’altro con il Bergson di Materia e memoria (la sua idea di immagine in sé: lacanianamente, una sorta di scheggia di reale, irrelato, autistico, allucinatorio) e con l’idea bergsoniana di gesto filosofico (che lo stesso Merleau-Ponty riprende, com’è noto, in Elogio della filosofia). L’idea guida è che un percorso psicoanalitico sia un’ontologia sperimentale: un esperimento con l’essere e dell’essere, e con un essere o di un essere risolto nel suo proprio sperimentarsi, nel suo proprio divenire per esperienze ed esperimenti, nel suo proprio accadere come scarto e nel suo proprio scartarsi. E che la filosofia, o almeno una certa idea di filosofia, quella dell’Elogio merleau-pontyano, proceda in analoga direzione. (shrink)

This article examines the place of literature in the ensemble of Merleau-Ponty’s research, comparing the function it fills in the economy of his thought to the role other practices and other disciplines such as biology and psychology play in his philosophy. Each of these “discourses” offered Merleau-Ponty access to something comparable to a common phantasmatic substance, a common metaphorical stability of Being, that the biologist, the writer, and the psychoanalyst work on, each in their own writings and categories. But here (...) emerges also a major question. To what extent does the language of Proust reveal itself up to the task of writing the phantasm, to what extent does it respond to this challenge? In what manner are the limits of his language, which are perhaps the limits of language itself, an obstacle to his project? And what is it that permits, at times, the sciences to obtain greater success in engaging in this way? Was it precisely the structure of metaphor that hindered Proust in truly writing encroachment, and the dimension of metonymy was, on the contrary, that in which a certain scientific discourse succeeded at setting itself up on the first try? If, finally and especially, metonymy was the very heart of metaphor, with more or less success touched by one or the other of the “regional” writings of the phantasm? (shrink)

Emerging evidence suggests that DNA topology plays an instructive role in cell fate control through regulation of gene expression. Transcription produces torsional stress, and the resultant supercoiling of the DNA molecule generates an array of secondary structures. In turn, local DNA architecture is harnessed by the cell, acting within sensory feedback mechanisms to mediate transcriptional output. MYC is a potent oncogene, which is upregulated in the majority of cancers; thus numerous studies have focused on detailed understanding of its regulation. Dissection (...) of regulatory regions within the MYC promoter provided the first hint that intimate feedback between DNA topology and associated DNA remodeling proteins is critical for moderating transcription. As evidence of such regulation is also found in the context of many other genes, here we expand on the prototypical example of the MYC promoter, and also explore DNA architecture in a genome-wide context as a global mechanism of transcriptional control. Torsional stress, and supercoiling generated by transcription, shape the topology of DNA. Furthermore, the resultant secondary DNA structures and their interacting partners provide feedback to regulate gene expression. Emerging evidence suggests these mechanisms, identified through analysis of the MYC promoter, are applicable genome-wide. (shrink)

This article aims through a study of the epigraphy of Pope Damasus, to reconstruct the ideal society that was shown to the pilgrim who went to the loca sanctorum in the Urbs. Taking into account the pastoral, political and ideological elements of Damasian epigraphy, it shows that the choice of martyrs and subjects which were celebrated responded to the increasing numbers of nobles within Roman Christian society after the peace of Constantine. Damasus tried to accommodated himself to the sensibilities of (...) the minor aristocracy of Rome and the emerging clergy, without renouncing its hierarchical organization of the Church in line with the social and ecclesial tendencies of the second half of the fourth century, when Roma christiana came into being. (shrink)

A meditation on specularity as paradigms of a theory of experience which informs every field of philosophy and human sciences, including contemporary neurosciences. And a meditation, starting from neurosciences and mirror neurons, on the different readings of this paradigm of specularity and specularization. In particular, on that “second” reading of specularization, which suggests that the mirror is not an instrument of representation but of expression, not a device of adaquation but of creation. It is an hypothesis that Merleau-Ponty, facing the (...) very same problems contemporary neurosciences are confonted to, reactivates in an increasingly systematic way in his later years, drawing from a tradition which we try here to reconstruct. From Merleau-Ponty to Bergson, from Bergson to Leibniz, this second reading of specularity contains a possibility which is still fruitful and which neurosciences themselves could adopt in order to reconsider in a new perspective the evidences they have considered until now from the point of view of a first reading of specularity. This second reading of specularity suggests that it is not so much necessary to explain how one subject comprehends the other, but how both subjects are comprehended within the transcendental space of what we could call an event. Empathy is not so much a syntonization among subjects, but subjects are a partial and local desyntonization of that empathic system we should place as the beginining and not at the end of the process. Consciousness does not represent the other consciousness, but they express in a simultaneous and specular diffraction the fundamental unity of an event which is every time unique and impersonal. (shrink)